Grid design has been a growing trend in web design and were pioneered by Khoi Vinh, a Creative Director of NYTimes, and a talented web designer Mark Boulton from the UK in recent years. The Grid System is another great resource to help you get started in designing site using grids. The creator demonstrated the concept and implementation very well by putting together the site using... grid.

Well, it's a great resource, give it a look!

I implemented dnnGallery using the similar approach. But I think it's time to go back and a take a look at the pixel perfect in designing using grid for the site.